What primary physical process defines a star while it resides on the Main Sequence?
Answer
Fusing hydrogen into helium in their cores
Stars on the Main Sequence are in the longest, most stable phase of their life, characterized by the ongoing fusion of hydrogen into helium within their cores.

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HR Diagram Explained - Star Color, Temperature and Luminosity
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What two fundamental physical characteristics are mapped against each other on the H-R diagram?How is surface temperature represented on the standard H-R diagram's horizontal axis?What primary physical process defines a star while it resides on the Main Sequence?What characteristic primarily governs the position of a star along the Main Sequence band?Which region of the H-R diagram is occupied by Red Giants or Supergiants?What physical property resolves the apparent contradiction of Red Giants being both highly luminous and relatively cool?Where are White Dwarfs clustered on the H-R diagram?Why do White Dwarfs exhibit very low luminosity despite being extremely hot?What is the longest, most stable phase of stellar life represented on the H-R diagram?How is the H-R diagram utilized to determine the age of stars in a globular cluster?