What structural adaptation would hypothetical organisms need to maintain internal liquid water against near-zero external pressure?

Answer

Incredibly strong, rigid cell walls or internal hydrostatic skeletons.

To counteract the near-perfect external void, life would require robust internal structures, such as rigid cell walls or hydrostatic skeletons, capable of containing their internal fluids against the lack of external pressure.

What structural adaptation would hypothetical organisms need to maintain internal liquid water against near-zero external pressure?

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