What chemical class causes nerve depolarization and repetitive firing by acting as a sodium channel agonist?

Answer

Organochlorines and pyrethroids

Organochlorines and pyrethroids are noted for acting as sodium channel agonists, which leads to nerve depolarization and repetitive firing, causing symptoms like tremors and paresthesias.

What chemical class causes nerve depolarization and repetitive firing by acting as a sodium channel agonist?
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