Which property is critical for a microchip substrate but largely irrelevant when an enzyme acts on its substrate?

Answer

Electrical characteristics and flatness.

A microchip substrate must have precise electrical characteristics and flatness because it dictates device properties, whereas when an enzyme acts, the substrate's bulk physical properties are largely irrelevant beyond fitting the active site.

Which property is critical for a microchip substrate but largely irrelevant when an enzyme acts on its substrate?
BasesubstrateMaterialreactionenzyme