What is the typical outcome when DNA methylation occurs in CpG islands?

Answer

The gene is generally signaled to silence expression.

The addition of methyl groups to cytosine bases within regulatory regions known as CpG islands acts as a molecular deterrent, physically blocking transcription factors and resulting in gene silencing.

What is the typical outcome when DNA methylation occurs in CpG islands?

#Videos

Epigenetic Control of Gene Expression - YouTube

expressionEpigeneticgene