Defense articles
What is the primary role of inflammation in the body?
What action do chemical mediators released by mast cells initiate in the affected tissue?
Which elements exit the bloodstream due to increased capillary permeability during inflammation?
What physiological change causes the visible signs of redness and heat during inflammation?
What protective function does swelling (edema) serve?
What is the protective purpose of pain associated with inflammation?
How is the duration of beneficial acute inflammation generally characterized?
What specialized immune cells reside in the Central Nervous System (CNS) that initiate localized inflammatory responses?
Which chemical messengers orchestrate cellular activities and direct traffic during the inflammatory process?
What primarily differentiates the transition from protective acute inflammation to harmful chronic inflammation?
What is a significant negative consequence of sustained, chronic inflammation?
What types of subtle symptoms might indicate the presence of chronic inflammation?
What molecular signatures define the self/non-self distinction managed by the immune system?
What structures do innate immune cells possess to immediately spot molecular patterns conserved across broad classes of microbes?
What do Pattern Recognition Receptors (PRRs) recognize as molecular signals indicating an immediate microbial invasion?
On which types of cells are MHC Class I molecules primarily found?
What process is described by the elimination of developing T cells that bind too strongly to self-peptides presented on self-MHC molecules?
What criterion must a developing T cell meet during Positive Selection in the thymus to prove functionality?
Which primary lymphoid organ is responsible for the central education and tolerance training of T cells?
What peripheral tolerance mechanism renders a self-reactive T cell functionally unresponsive if it encounters its antigen without accompanying danger signals?
What term describes the condition resulting when the immune system fails to maintain self/non-self balance and attacks host cells?